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RESEARCH INTERESTS: Reproductive Physiology of Lower Vertebrates RESEARCH SUMMARY: I am a comparative physiologist interested in the physiology
of fish gametes, the effect of endocrine disrupting chemicals
on reproductive aspects of the lower vertebrates and in maternal-fetal
interactions in viviparous vertebrates. Recently, we have focused
our research on understanding the role of adenosine triphosphate
(ATP) in salmonid sperm and egg motility and fertility and on
the ability and mechanism of carbon dioxide to reversibly inhibit
sperm motility. ATP turns over quickly in the sperm and we are
examining whether this turnover (and its associated requirement
for nutrient usage) is reduced in vivo by carbon dioxide from
normal metabolism in the male. In addition, we have been examining
the role(s) and fate of extracellular ATP, are involved in studies
of the effects of endocrine disrupting chemicals on embryonic
and larval development and function in amphibians and maintain
interests in elucidating the mechanisms involved in gas and nutrient
transfer to the fetus in viviparous snakes.
David Bencic, a graduate student in Dr. Ingermann's laboratory, is holding adult female Pacific Northwest Garter Snakes.
REPRESENTATIVE PUBLICATIONS: Ingermann, RL, Robinson, ML, Cloud, JG. 2003. Respiration of steelhead trout sperm: sensitivity to pH and carbon dioxide. J. Fish Biol. 62: 13-23. Ingermann RL, Bencic DC, Verrell P. 2002 Methoxychlor alters the predator-prey relationship between dragonfly naiads and salamander larvae. Bull Environ Contam Toxicol. 68(6):771-8. Eroschenko VP, Amstislavsky SY, Schwabel H, Ingermann RL. 2002 Altered behaviors in male mice, male quail, and salamander larvae following early exposures to the estrogenic pesticide methoxychlor. Neurotoxicol Teratol. 24(1):29-36.. Bencic, D.C., R. L. Ingermann and J. G. Cloud. 2001. Does CO2 enhance short-term storage success of chinook salmon (Oncorhynchus tshawytscha) milt? Theriogenology 56:157-166. Bencic, D.C., J. G. Cloud and R. L. Ingermann. 2000. Carbon dioxide reversibly inhibits sperm motility and fertilizing ability in steelhead trout (Oncorhynchus mykiss). Fish Physiology and Biochemistry 23:275-281. Bencic, D.C., M. Krisfalusi, J.G. Cloud, and R.L. Ingermann (1999). ATP levels of chinook salmon (Oncorhynchus tshawytscha) sperm following in vitro exposure to various oxygen tensions. Fish Physiol. Biochem. 20:389-397 \Ingermann, R.L., D.C. Bencic, and V.P. Eroschenko (1999). Methoxychlor effects on hatching and larval startle response in the salamander Ambystoma macrodactylum are independent of its estrogenic actions. Bull. Environ. Contam. Toxicol. 62: 578-583 Ingermann, R.L., D.C. Bencic, and V.P. Eroschenko (1997). Methoxychlor alters hatching and larval startle response in the salamander Ambystoma macrodactylum. Bull. Environ. Contam. Toxicol. 59: 815-821 Bencic, D.C., T.J. Yates, and R.L. Ingermann (1997). Ecto-ATPase activity of vertebrate blood cells. Physiol. Zool. 70: 621-630. Ingermann, R.L. Vertebrate hemoglobins. Handbook of Physiology. Am. Physiol Soc., Sect 13, pp. 357-408. Herman, J.K. and R.L. Ingermann (1996). Effects of hypoxia on oxygen-transfer properties of the blood of a viviparous snake. J. Exp. Biol. 199:2061-2070 Ragsdale, F.R., J.K. Herman, and R.L. Ingermann (1995). Nucleoside triphosphate levels versus oxygen affinity of rattlesnake red cells. Respir. Physiol. 102:63-69. Ragsdale, F.R. and R.L. Ingermann (1993). Biochemical bases for difference in oxygen affinity of maternal and fetal red cells of rattlesnakes. Am. J. Physiol. 264:R481-R486. Ragsdale, F.R., K.M. Imel, E.E. Nilsson, and R.L. Ingermann (1993). Pregnancy-associated factors affecting organic phosphate levels and oxygen affinity of garter snake red cells. Gen. Comp. Endocrinology 91:181-188. Ingermann, R.L. (1992). Maternal-fetal oxygen transfer in lower vertebrates. Am. Zool. 32:322-330. |
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