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Phone: 509-335-8761 Fax: 509-335-4246 Email:jiangz@wsu.edu
RESEARCH SUMMARY: My research interest in reproductive genomics includes mapping of quantitative trait loci (QTL) and transcriptomes for genetic complexity of female reproduction. We use both candidate gene and genome-wide scanning approaches in identifying genes or genome regions that are responsible for various complex traits related to ovulation, embryo survival and pregnancy. In transcriptome analysis, we use a gene-based approach to study the gene expression patterns of different reproductive tissues/organs in mammalian species. We focus on gene clustering analysis, which enables us to gain insight into possible common regulatory factors and pathways involved in reproduction. A new initiative is to generate in silico whole genome association maps for different reproductive diseases. REPRESENTATIVE PUBLICATIONS: Jiang Z, Michal JJ, Melville JS, Baltzer HL. 2005. Multi-alignment of orthologous genome regions in five species provides new insights into the evolutionary makeup of mammalian genomes. Chromosome Research 13:707-715. Jiang Z, Wu X-L, Garcia MD, Griffin KB, Michal JJ, Ott TL, Gaskins CT, Wright Jr. RW. 2004. Comparative gene-based in silico transcriptome analysis of different tissues/organs in cattle. Genome 47:1164-1172. Jiang Z, Zhang M, Wasem VD, Michal JJ, Zhang H, Wright Jr. RW. 2003. Census of genes expressed in porcine embryos and reproductive tissues by mining EST database based on the human genes. Biology of Reproduction 69:1177-1182. King AM, Jiang Z, Gibson JP, Haley CS, Archibald AL. 2003. Mapping quantitative trait loci affecting female reproductive traits on porcine chromosome 8. Biology of Reproduction 68:2172-2179. Jiang Z, Gibson JP, Archibald AL, Haley CS. 2001. The porcine gonadotropin-releasing
hormone receptor (GnRHR) gene: genomic organization, genetic polymorphisms
and association with prolificacy. Genome 44:7-12.
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