Professor Animal Sciences

Dept. of Animal & Vet. Sciences

114 New Exptl. Animal Laboratory Building
Washington State University
Pullman WA 99164-6351

Phone: 509-335-0165

FAX: 509-335-4246

E-mail: ristow@uidaho.edu

 

Ph.D., 1972

University of Minnesota

RESEARCH INTERESTS:

Fish Immunology

RESEARCH SUMMARY:

The primary emphasis of my research program is the study of the immune systems of salmonid fish and their specific and nonspecific responses to viral disease. With the advent of intensive aquaculture practices, it is important to augment the fish immune system to ward off disease under conditions of stress. My laboratory has studied the infectious hematopoitic necrosis virus and the response of the trout to this pathogen. In addition, we have been studying, as models for fish disease research, the immune systems of the homozygous clones of rainbow trout produced in Gary Thorgaard's laboratory in the Division of Biological Sciences. Our interest in fish reproduction is in optimizing vaccination regimens that would not compromise the efficiency of reproduction and that would immunize the progeny as a result of parental vaccination.

REPRESENTATIVE PUBLICATIONS:

Zhang H, JP Evenhuis, GH Thorgaard, SS Ristow. Cloning, characterization and genomic structure of the natural killer cell enhancement factor (NKEF)-like gene from homozygous clones of rainbow trout (Oncorhynchus mykiss). Developmental and Comparative Immunology, 25:25-35, 2001.

Ristow SS, SE LaPatra, R Dixon, CR Pedrow, WD Shewmaker, J-W Park, GH Thorgaard. Responses of cloned rainbow trout to an attenuated strain of infectious hematopoietic necrosis virus. Diseases of Aquatic Organisms, 42(3):163-172, 2000.

Zhang H, B Robison, G Thorgaard, SS Ristow. Cloning, mapping and genomic organization of a fish C-type lectin gene from homozygous clones of rainbow trout (Oncorhynchus mykiss). Biochimica et Biophysica Acta, 1494:14-22, 2000.

Cain KD, Byrne KM, Brassfield AL, Lapatra SE, & Ristow SS. Temperature dependent characteristics of a recombinant infectious hematopoietic necrosis virus glycoprotein produced in insect cells. Diseases Of Aquatic Organisms 36:1-10, 1999.

Cain KD, Lapatra SE, Shewmaker B, Byrne KM, & Ristow SS. Immunogenicity of a recombinant infectious hematopoietic necrosis virus glycoprotein produced in insect cells. Diseases of Aquatic Organisms 36:67-72, 1999.

Ristow SS, Warr GW, Kaattari Sl, De Avila J, Thorgaard GH. Coding sequences of the mhc ii beta chain of isogenic trout. Developmental and Comparative Immunology 23:51-60. 1999.

Ristow SS, Grabowski LD, Ostberg C, Robison B, Thorgaard GH. development of long term cell lines from homozygous rainbow trout. Journal of Aquatic Animal Health 10:75-82, 1998.