J. Adam Luckenbach
|Department:||Northwest Fisheries Science Center|
|Credentials:||2004 - Ph.D., North Carolina State University; Department of Zoology|
|Mailing Address:||Environmental Physiology Program|
Northwest Fisheries Science Center
2725 Montlake Blvd. East
Seattle, WA 98112
Sex control and regulation of gametogenesis in fishes
Fish exhibit a high degree of plasticity in their mechanisms of sex determination. My previous research focused on environmental sex determination (ESD) in flounder, which exhibit a unique form of sex determination where both genetic and environmental factors, such as water temperature, can influence their phenotypic sex. Currently, my lab has several projects focusing on sex determination and gonadal differentiation, hormonal sex control, and reproduction in sablefish (also known as black cod), a high-value marine species native to the North Pacific Ocean. The overarching goals of these projects are to gain a basic understanding of fish reproductive development and to develop non-GMO approaches for sex control (e.g., induction of sterility or monosex stocks) of marine fishes for aquaculture. The ability to produce sterile marine fishes would greatly reduce escapement risks associated with cultured fish by preventing genetic contamination of wild stocks. It is also possible that sterile fish may exhibit superior aquaculture performance relative to fertile fish.
Luckenbach JA, Fairgrieve WT, ES Hayman. 2017. Establishment of monosex female production of sablefish (Anoplopoma fimbria) through direct and indirect sex control. Aquaculture 479: 285-296.
Fairgrieve, MR, Shibata Y, Smith EK, Hayman ES, JA Luckenbach. 2016. Molecular characterization of the gonadal kisspeptin system: cloning tissue distribution, gene expression analysis and localization in sablefish (Anoplopoma fimbria). General and Comparative Endocrinology 225: 212-223.
Luckenbach JA, Yamamoto Y, Guzmάn JM, P. Swanson. 2013. Identification of ovarian genes regulated by follicle-stimulating hormone (Fsh) in vitro during early secondary oocyte growth in coho salmon. Molecular and Cellular Endocrinology 3696: 38-52.
Smith EK, Guzmάn JM, JA Luckenbach. 2013. Molecular cloning, characterization and sexually dimorphic expression of five major sex differentiation-related genes in a Scorpaeniform fish, sablefish (Anoplopoma fimbria). Comparative Biochemistry and Physiology Part B 165: 125-137.
Luckenbach JA, RJ Borski, HV Daniels and J Godwin. 2009. Sex determination in flatfishes: mechanisms and environmental influences. Seminars in Cell and Developmental Biology 20: 256-263.