Participating Faculty

Stephen White

Stephen White

Department:USDA-ARS, Animal Disease Research Unit
Office:3003 ADBF
Phone:509-335-7407
Fax:509-335-8328
Mailing Address:PO Box 646630
Pullman, WA 99164-6630
E-mail:stephen.white@wsu.edu or stephen.white@ars.usda.gov
Website:Click here


Research Interests

Comparative and functional genomics, genetics of susceptibility to infectious disease, inherited disease, genetics of reproduction

Research Summary

Dr. White’s primary research interest is in genetics of host-pathogen interactions and ways to use genetics to reduce animal disease. Current projects include genetics of susceptibility to reproductive pathogens, ruminant respiratory pathogens, transmissible spongiform encephalopathies including scrapie, reproductive performance in domestic ruminants, and functional annotation of animal genomes. 

Research Publications

Cinar, M.U., Schneider, D.A., Waldron, D.F., O’Rourke, K.I., White, S.N. Goats singly heterozygous for PRNP S146 or K222 orally inoculated with classical scrapie at birth show no disease at ages well beyond six years. The Veterinary Journal. (In press)

Kiser, J.N., Neupane, M., White, S.N., Neibergs, H.L. Identification of genes associated with susceptibility to Mycobacterium avium ssp. paratuberculosis (Map) tissue infection in Holstein cattle using gene set enrichment analysis-SNP. Mammalian Genome. (In press)

Wise, L.N., Kappmeyer, L.S., Silva, M.G., White, S.N., Grause, J.F., Knowles, D.P. Verification of post chemotherapeutic clearance of Theileria equi through concordance of nested PCR and immunoblot. Ticks & Tick-Borne Diseases 9(2):135-140. 2018.

Oliveira, R.D., Mousel, M.R., Pabilonia, K.L., Highland, M.A., Taylor, J.B., Knowles, D.P., White, S.N. Domestic sheep show average Coxiella burnetii seropositivity generations after a sheep-associated human Q fever outbreak but lack detectable shedding by placental, vaginal, and fecal routes. PLoS One 12(11):e0188054. 2017.

White, S.N., Oliveira, R.D., Mousel, M.R., Gonzalez, M.V., Highland, M.A., Herndon, M.K., Taylor, J.B., Knowles, D.P. Underdominant KCC3b R31I association with blood sodium concentration in domestic sheep suggests role in oligomer function. Animal Genetics 48(5):626-627. 2017.

Mason, K.L., Gonzalez, M.V., Chung, C., Mousel, M.R., White, S.N., Taylor, J.B., Scoles, G.A. Detection of Anaplasma ovis and validation of improved A. marginale cELISA kit for diagnostic use in domestic sheep. Journal of Veterinary Diagnostic Investigation. 29(5):763-766. 2017.

Kiser, J.N., White, S.N., Johnson, K.A., Hoff, J., Taylor, J.F., Neibergs, H.L. Identification of loci associated with susceptibility to Mycobacterium avium subspecies paratuberculosis (Map) tissue infection in cattle. Journal of Animal Science. 95(3):1080-1091. 2017.

Batra, S.A., Shanthalingam, S., Donofrio, G., Haldorson, G.J., Chowdhury, S., White, S.N., Subramaniam, S. Immunization of bighorn sheep against Mannheimia haemolytica with a bovine herpesvirus 1-vectored vaccine. Vaccine. 35(12):1630-1636. 2017. 
Cinar, M.U., Mousel, M.R., Herrmann-Hoesing, L.M., Taylor, J.B., White, S.N. Ovar-DRB1 haplotypes *2001 and *0303 are associated with sheep growth and ewe lifetime prolificacy. GENE 595(2):187-192. 2016.

Tuggle, C.K., Giuffra, E., White, S.N., Clarke, L., Zhou, H., Ross, P.J., Acloque, H., Reecy, J.M., Archibald, A., Tixier-Boichard, M., Chamberlain, A., Cheng, H., Croojimans, R.P.M.A., Delany, M.E., Groenen, M.A.M., Hayes, B., Lunney, J.K., Plastow, G.S., Silverstein, J., Song, J., Watson, W. GO-FAANG meeting: a Gathering on Functional Annotation of ANimal Genomes. Animal Genetics 47(5):528-533. 2016.

Highland, M.A., Schneider, D.A., White, S.N., Madsen-Bouterse, S.A, Knowles, D.P., Davis, W.C. Single-label flow cytometry using cross reactive monoclonal antibodies identifies leukocyte surface molecule abundance differences in domestic sheep (Ovis aries) and bighorn sheep (Ovis canadensis) neutrophils. Comp Immunol Microbiol Infect Dis. 46:40-46. 2016.

Mousel, M.R., White, S.N., Herndon, D.R., Reynolds, J.O., Gonzalez, M.V., Johnson, W.C., Ueti, M.W., Taylor, J.B., Knowles, D.P. Ovine leukocyte profiles do not associate with variation in the prion gene, but are breed dependent. Animal Genetics 47(1):136-137. 2016.

 

Washington State University